Study note

Additional pilocarpine uses and muscarine

THE CONTEXT
This passage continues the discussion of pilocarpine as an ocular miotic and introduces muscarine as a mushroom toxin.

Pilocarpine

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Initial ocular stinging and painful spasm of accommodation are frequent adverse effects.
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Pilocarpine can counteract mydriatics after their use for testing refraction.
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Alternating pilocarpine with mydriatics can prevent or break adhesions of the iris with the lens or cornea.
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It can act as a sialogogue, but the source states that no oral preparation is available.

Muscarine and mushroom poisoning

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Muscarine occurs in poisonous mushrooms, including Amanita muscaria and Inocybe species, and has only muscarinic actions.
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Muscarine has toxicological importance but is not used therapeutically.
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At least three types of mushroom poisoning are recognized according to the toxic principle present.
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