Study note
Biochemistry
Micronutrients: Vitamins & Minerals
Assessment of thiamin status by erythrocyte transketolase activation
THE CONTEXT
Thiamin nutritional status
can be assessed using an enzyme activation procedure in erythrocyte lysate.
Accepted assessment
•
Thiamin diphosphate
is added in vitro to erythrocyte lysate to activate apotransketolase, the enzyme protein.
•
This activation
is an accepted index of thiamin nutritional status.
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