Study note

Assessment of thiamin status by erythrocyte transketolase activation

THE CONTEXT
Thiamin nutritional status can be assessed using an enzyme activation procedure in erythrocyte lysate.

Accepted assessment

•
Thiamin diphosphate is added in vitro to erythrocyte lysate to activate apotransketolase, the enzyme protein.
•
This activation is an accepted index of thiamin nutritional status.
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