Study note

Bundle branch block: conduction changes, hemiblock and clinical significance

THE CONTEXT
Damage to ventricular conducting branches alters the route and timing of ventricular depolarisation. Complete bundle branch block and fascicular block produce different electrocardiographic changes.

Causes and conduction mechanism

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Bundle branch damage may result from ischaemic heart disease, hypertensive heart disease or cardiomyopathy.
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Right bundle branch block (RBBB)* can also be a normal variant in healthy individuals.
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In RBBB and left bundle branch block (LBBB), depolarisation in the affected ventricle proceeds through slow myocardium instead of rapidly conducting Purkinje tissue.
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Delayed ventricular conduction broadens the QRS complex to at least 0.12 seconds and produces characteristic changes in QRS morphology.

Hemiblock and bifascicular block

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Damage after the left bundle divides into its anterior and posterior fascicles is called hemiblock.
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In hemiblock, the QRS remains narrow, but the direction of ventricular depolarisation changes.
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Left anterior hemiblock causes left axis deviation; left posterior hemiblock causes right axis deviation.
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RBBB combined with either left anterior or left posterior hemiblock is called bifascicular block.

LBBB findings and clinical implications

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LBBB often signifies underlying heart disease and causes ventricular incoordination that may aggravate heart failure symptoms.
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Selected patients can be treated with cardiac resynchronisation therapy pacemakers.
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The described LBBB electrocardiogram has wide QRS complexes, loss of the Q wave or septal vector in lead I, and M-shaped QRS complexes in V5 and V6.

Atrial ectopic beat appearance

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The accompanying atrial ectopic beat description identifies abnormal, sometimes barely visible, P waves with QRS complexes identical to those of the normal sinus beats.
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