Study note

Chronic hypertension in pregnancy: fetal risks and management

THE CONTEXT
The passage relates fetal and perinatal risks to the severity of chronic hypertension and outlines blood pressure treatment and obstetric management.

Fetal and perinatal risks

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Chronic placental insufficiency makes fetal growth restriction likely, and preterm birth is high.
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In milder disease with blood pressure below 160/100 mm Hg, perinatal loss is about 10%.
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When blood pressure exceeds 160/100 mm Hg, perinatal loss increases three to four times and rises further if pre-eclampsia develops.
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The risk of placental abruption is high, with a stated range of 0.5–10%.

Management goals and preconception assessment

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Management aims to stabilize blood pressure below 160/100 mm Hg, prevent superimposed pre-eclampsia, monitor maternal and fetal wellbeing and deliver at the optimal time.
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Preconception evaluation and counseling are essential to assess the cause and severity of hypertension and the possible pregnancy outcome.

Antihypertensive treatment

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Routine antihypertensive treatment is not favored in the passage: lowering blood pressure may benefit the mother while reducing placental perfusion to the detriment of the fetus.
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Labetalol, nifedipine or hydralazine should be used when blood pressure rises beyond 160/100 mm Hg to prevent target organ damage, including stroke and renal or cardiac failure.
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For women taking these drugs before pregnancy, doses require adjustment during pregnancy, especially in midpregnancy when blood pressure tends to fall.

Obstetric and postpartum management

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In mild cases, spontaneous labor is awaited.
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In severe or complicated cases, the stated aim is to continue pregnancy to at least 34 weeks; otherwise, pregnancy is continued up to the 37th week to attain fetal maturity before delivery.
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Blood pressure control is needed for the first 24 hours postpartum.
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