Study note

Investigations for myocarditis

THE CONTEXT
Myocarditis is often diagnosed after more common causes of cardiac dysfunction have been excluded. Imaging, blood markers and occasionally biopsy support assessment.

Cardiac imaging

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Echocardiography should be performed and may show left ventricular dysfunction. Dysfunction can be regional when myocarditis is focal.
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Cardiac MRI may show diagnostic patterns of myocardial inflammation or infiltration.

Electrical findings and cardiac injury markers

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The ECG is frequently abnormal, but its changes are nonspecific.
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Cardiac troponin I or T should be assessed in blood and can be used to monitor the severity and progression of cardiac injury and myocarditis.

Diagnostic confirmation

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Endomyocardial biopsy is occasionally required to confirm the diagnosis.
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