Long-term health outcomes after severe pre-eclampsia
THE CONTEXT
Severe pre-eclampsia is associated with risks in subsequent pregnancies and later cardiovascular, renal, and metabolic health.
Subsequent pregnancy outcomes
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Future pregnancies carry increased risks of pre-eclampsia, placental abruption, fetal growth restriction, and spontaneous or indicated preterm birth.
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Women with HELLP syndrome have a higher risk of recurrence.
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Recurrent pre-eclampsia is listed at 25%.
Later health outcomes
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Cardiovascular outcomes include chronic hypertension, cardiomyopathy, ischemic heart disease, and coronary artery disease. Cardiovascular disease risk is increased later in life.
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Renal outcomes include glomerular dysfunction and chronic renal disease.
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Retinal detachment, type 2 diabetes, and obesity are also listed among remote health outcomes.
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Metabolic syndrome is included; the stated common underlying pathologies are thrombophilias, insulin resistance, or preexistent renal disease.
Risk-reducing interventions
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The passage lists a healthy diet, avoidance of smoking, weight loss, and aspirin therapy as interventions that improve outcomes.
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Management of hypertension, type 2 diabetes, thrombophilias, and dyslipidemia is also included.