Study note
SurgeryThe thyroid gland

Management of large toxic nodular goitre

THE CONTEXT
Goitre size and its response to nonsurgical treatment influence management of toxic nodular goitre.

Size and treatment response

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Toxic nodular goitre is often large and uncomfortable, and it can enlarge further with antithyroid drugs.
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Compared with diffuse toxic goitre, large toxic nodular goitres respond less well and less rapidly to radioiodine or antithyroid drugs.

Preferred management

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Large toxic nodular goitres should be treated surgically.
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