Study note
MedicineCardiology

Medical therapy for peripheral arterial disease

THE CONTEXT
Medical management combines lifestyle measures, antithrombotic treatment, cholesterol reduction and treatment of associated conditions.

Lifestyle measures

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Stop smoking.
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Undertake regular exercise: 30 minutes of walking three times per week.
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Address diet and weight loss.

Drug therapy

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Use an antiplatelet agent: aspirin 75 mg daily or clopidogrel 75 mg daily.
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Consider the low-dose factor Xa inhibitor rivaroxaban at 2.5 mg twice daily.
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Use statins to reduce cholesterol.

Associated conditions

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Diagnose and treat diabetes mellitus.
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Diagnose and treat associated hypertension, anaemia and heart failure.
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