Study note

Myocarditis: clinical forms and outcomes

THE CONTEXT
Myocarditis has four described clinical presentations and is self-limiting in most patients, although serious acute and delayed complications can occur.

Four clinical presentations

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Fulminant myocarditis: follows a viral prodrome or influenza-like illness and causes severe heart failure or cardiogenic shock.
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Acute myocarditis: presents over a longer period with heart failure and can lead to dilated cardiomyopathy.
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Chronic active myocarditis: is rare and associated with chronic myocardial inflammation.
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Chronic persistent myocarditis: features focal myocardial infiltrates and can cause chest pain and arrhythmia without necessarily causing ventricular dysfunction.

Prognosis and complications

FeatureDetails
Usual course
myocarditis is self-limiting in most patients, with a good immediate prognosis.
Fatal complications
death may result from ventricular arrhythmia or rapidly progressive heart failure.
Young athletes
myocarditis has been reported as a cause of sudden and unexpected death.
Long-term disease
some forms progress to chronic low-grade myocarditis or dilated cardiomyopathy.
Chagas disease
patients frequently recover from the acute infection but develop chronic dilated cardiomyopathy 10 or 20 years later.
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