Study note
Obstetrics & GynecologyHypertensive Disorders in Pregnancy

Neurological, hepatic, platelet and renal severe features

THE CONTEXT
These abnormalities are listed among the severe features of pre-eclampsia or gestational hypertension.

Central nervous system dysfunction

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Visual disturbances include photopsia, blurred vision, scotomata, cortical blindness and retinal vasospasm.
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Neurological features include severe headache or headache that persists and progresses despite analgesia, altered mental status and stroke.

Hepatic abnormality

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Severe persistent right upper quadrant or epigastric pain that is unresponsive to medication is a listed hepatic feature.
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Elevated serum transaminase concentration is also included among hepatic abnormalities.

Thrombocytopenia

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The listed platelet count threshold is less than 100,000 platelets/µL.

Renal abnormality

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Progressive renal insufficiency includes serum creatinine greater than 1.1 mg/dL.
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Doubling of serum creatinine concentration in the absence of other renal disease is another listed renal abnormality.
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