Nicotinic actions of acetylcholine on autonomic ganglia

THE CONTEXT

Acetylcholine stimulates autonomic ganglia, with this effect becoming evident at higher doses.

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Both sympathetic and parasympathetic ganglia are stimulated.

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A high dose of acetylcholine administered after atropine produces tachycardia and a rise in blood pressure.

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This cardiovascular response results from sympathetic ganglion stimulation and catecholamine release.

NEETx

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