The burden of coronary artery disease (CAD) and the degree of left ventricular dysfunction determine prognosis.
Disease extent and ventricular function
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Single-vessel disease with good left ventricular function is associated with five-year survival above 90%.
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Severe left ventricular dysfunction with extensive three-vessel disease is associated with five-year survival below 30% unless revascularisation is performed.
Symptoms and mortality
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Symptoms are a poor guide to prognosis overall.
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Nevertheless, patients with severe angina, classified as CCS angina scale III or IV, have nearly twice the five-year mortality of patients with mild symptoms.