Study note

Syphilitic otitis media: spread, manifestations, diagnosis and treatment

THE CONTEXT
Syphilitic otitis media is rare and can involve both the middle ear and the sensory structures of the inner ear.

Routes of infection

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Spirochaetes reach the middle ear through the eustachian tube when syphilitic lesions are present in the nose or nasopharynx.
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Infection may also be blood-borne.

Manifestations and tissue damage

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Spirochaetes soon invade the sensory end organs of the inner ear and their nerves, causing profound sensorineural hearing loss, tinnitus and vertigo.
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Bone necrosis and sequestrum formation are common and cause foetid ear discharge.
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Secondary pyogenic infection may produce a clinical picture resembling chronic suppurative otitis media.

Diagnostic tests

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Definite diagnosis requires specific treponemal antigen tests, such as the treponemal pallidum immobilization (TPI) test and fluorescent treponemal antibody absorption test (FTA-ABS).
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VDRL and RPR tests are nonspecific but useful for monitoring disease; false positive results may occur.

Treatment

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Treatment consists of antisyphilitic therapy, aural toilet and control of secondary infection.
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Surgery may be required to remove sequestra.
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