Study note

Systematic interpretation of a 12-lead ECG

THE CONTEXT
A structured ECG examination reviews rhythm, axis, atrial activity, conduction, ventricular complexes and repolarisation, using standard recording conventions.

Rhythm, axis and P waves

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Use the lead II rhythm strip to determine heart rate and rhythm.
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The cardiac axis is normal when QRS complexes are positive in leads I and II.
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Tall P waves denote right atrial enlargement (P pulmonale), while notched P waves denote left atrial enlargement (P mitrale).

PR interval and QRS complex

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The normal PR interval is 0.12–0.20 seconds. Prolongation denotes impaired atrioventricular nodal conduction; a short PR interval occurs in Wolff–Parkinson–White syndrome.
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A QRS duration greater than 0.12 seconds indicates abnormal ventricular conduction, including left or right bundle branch block.
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Large QRS complexes occur in slim young patients and in patients with left ventricular hypertrophy.
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Q waves may signify previous myocardial infarction.

ST segment, T waves and QT interval

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ST elevation may signify myocardial infarction, pericarditis or left ventricular aneurysm. ST depression may signify ischaemia or infarction.
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T-wave inversion has several causes, including myocardial ischaemia or infarction and electrolyte disturbances.
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The heart-rate-corrected QT interval is normally less than 0.44 seconds in males and 0.46 seconds in females.
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QT prolongation may occur with congenital long QT syndrome, low potassium, magnesium or calcium, and some drugs.

Recording conventions and rate calculation

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Depolarisation towards an electrode produces a positive deflection; depolarisation away produces a negative deflection.
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Standard sensitivity is 10 mm per 1 mV, and paper speed is 25 mm per second.
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A large 5 mm square represents 0.2 seconds; a small 1 mm square represents 0.04 seconds.
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Heart rate equals 1500 divided by the RR interval in millimetres, or 300 divided by the number of large squares between beats.
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