Study note

Thyroid function testing in discrete thyroid swellings

THE CONTEXT
Biochemical assessment identifies whether a discrete thyroid swelling is associated with hyperthyroidism and guides functional imaging.

Biochemical assessment

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Measure serum TSH and thyroid hormone levels.
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Biochemically confirmed hyperthyroidism with a discrete swelling indicates either a toxic adenoma or a manifestation of toxic multinodular goitre.

Functional localization

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The combination of toxicity and nodularity is an indication for isotope scanning to localize the areas of hyperfunction.
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