Study note
Surgery
The thyroid gland
Thyroid histology in hyperthyroidism
THE CONTEXT
Hyperthyroidism changes both the acinar epithelium and the appearance of thyroid colloid.
Normal thyroid
•
Normal thyroid acini have a cuboidal epithelial lining and
contain homogeneous colloid.
Hyperthyroid thyroid
•
The acini show hyperplasia and
are lined by high columnar epithelium.
•
Many acini
are empty; others contain vacuolated colloid with characteristic scalloping adjacent to the thyrocytes.
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