Study note
Obstetrics & Gynecology
Hypertensive Disorders in Pregnancy
Vascular sensitivity and nitric oxide synthesis
THE CONTEXT
The discussion of pre-eclampsia describes altered sensitivity to a pressor agent and identifies the sites and substrate of nitric oxide synthesis.
Vascular sensitivity
•
Vascular sensitivity to the pressor agent angiotensin
is increased.
Nitric oxide synthesis
•
Nitric oxide
is synthesized from L-arginine in the vascular endothelium and syncytiotrophoblast.
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