Adjuvant actions: prolonged antigen release and macrophage activation
THE CONTEXT
The passage describes ways in which adjuvants prolong antigenic stimulation or activate macrophages.
Prolonging antigenic stimulation
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Aluminium hydroxide and aluminium phosphate are listed as adjuvants.
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Protein antigens incorporated into the water phase of a water-in-oil emulsion are released more slowly from the injection site, prolonging the antigenic stimulus.
Macrophage activation
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Silica particles, beryllium sulphate and endotoxins activate macrophages.