Study note

CSFs in blood cell production and the types of TNF

THE CONTEXT
The passage describes how colony-stimulating factors meet changing blood cell requirements and introduces tumour necrosis factor.

Physiological and clinical roles of CSFs

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Colony-stimulating factors (CSFs) adjust the rate of blood cell production according to requirements.
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The massive granulocyte response in pyogenic infections is an example of this adjustment.
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CSFs have clinical applications in treating hematopoietic dysfunctions in infections and malignancies.

Tumour necrosis factor

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Tumour necrosis factor (TNF)* occurs as two types: alpha and beta.
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