Study note
MicrobiologyImmune Response

Cytokine signals supporting B cell activation

THE CONTEXT
The passage describes cytokine production and the subsequent proliferation and differentiation of antigen-bound B cells.

Cytokine sources

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The APC produces interleukin-1 (IL-1).
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The activated helper T cell produces interleukin-2 and other cytokines required for B cell stimulation, including IL-4, IL-5 and IL-6.

B cell response

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The described cytokines provide B cell activation and differentiation signals.
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B cells that have combined with their respective antigens undergo clonal proliferation and differentiate into antibody-secreting plasma cells.
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