Study note
MicrobiologyImmune Response

Host factors affecting immunological tolerance

THE CONTEXT
The ease of inducing tolerance varies with the host's species, strain and degree of immunocompetence.

Host variation

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Strain differences in tolerance induction occur within species.
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Rabbits and mice can be rendered tolerant more rapidly than guinea pigs and chickens.

Immunocompetence and age

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The greater the host's immunocompetence, the more difficult it is to induce tolerance.
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Embryos and newborns are particularly susceptible to tolerance induction because of this relationship with immunocompetence.
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