Study note

Instructive versus selective theories of immunity

THE CONTEXT

Theories of immunity are divided into instructive and selective categories according to the specificity attributed to immunocompetent cells.

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Instructive theories propose that an immunocompetent cell can synthesise antibodies of any specificity.

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Selective theories shift emphasis from the antigen to the immunocompetent cell and propose that such cells have a restricted immunological range.

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