Study note

Three steps of antibody production

THE CONTEXT

Antibody production proceeds through an afferent limb, central functions, and an efferent limb.

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The afferent limb comprises antigen entry, its distribution and fate in tissues, and contact with appropriate immunocompetent cells.

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Central functions comprise cellular processing of antigen and control of antibody formation.

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The efferent limb comprises antibody secretion, distribution in tissues and body fluids, and manifestation of antibody effects.

NEETx

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