Study note
MicrobiologyImmune Response

Transfer factor and antigen-specific transfer of immunity

THE CONTEXT
Transfer factor (TF) is a leucocyte extract associated with passive transfer of cell-mediated immunity (CMI).

Passive transfer and specificity

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Passive transfer of CMI was first achieved by injecting viable leucocytes from sensitised donors.
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The leucocyte extract is called transfer factor.
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Transferred immunity is specific: CMI can be transferred only to antigens to which the donor is sensitive.
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