Medicine chapter
MEDICINE

Infectious disease

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Questions

QUESTION 41
Which physical finding is more common in CMV infection than in infectious mononucleosis?
QUESTION 42
Which intracranial complication can result from mid-facial staphylococcal cellulitis?
QUESTION 43
How can Staphylococcus aureus cause severe systemic disease in the absence of bacterial tissue invasion?
QUESTION 44
An adult woman with rubella develops a relatively common joint manifestation. Which joint distribution is characteristic?
QUESTION 45
For how long after completing miltefosine treatment for visceral leishmaniasis should a female patient avoid pregnancy?
QUESTION 46
What is the role of ritonavir in the nirmatrelvir–ritonavir combination used for COVID-19?
QUESTION 47
Which cestode is listed both as an intestinal tapeworm and as a tissue-dwelling cyst or worm?
QUESTION 48
What is the only known reservoir for visceral leishmaniasis in major South Asian foci with anthroponotic transmission?
QUESTION 49
Which smear examination is described as the most efficient means of diagnosing visceral leishmaniasis, with 98% sensitivity?
QUESTION 50
In which region is lymphadenopathy rare in patients with visceral leishmaniasis?
QUESTION 51
Which organism serves as the intermediate host in the Schistosoma life cycle?
QUESTION 52
Which parasite is classified as a tissue-dwelling human nematode?
QUESTION 53
Which parasite is classified as an intestinal fluke?
QUESTION 54
Which investigation is at least 95% sensitive and accurately tracks recovery and relapse in HIV-associated visceral leishmaniasis?
QUESTION 55
Which stage of Schistosoma penetrates human skin during exposure to contaminated fresh water?
QUESTION 56
A hospitalised patient with COVID-19 requires supplemental oxygen. Which dexamethasone regimen is stated to improve survival?
QUESTION 57
For prevention of thromboembolism in COVID-19, which anticoagulation strategy is recommended?
QUESTION 58
Which regimen is used as first-line therapy for visceral leishmaniasis in the Kala-azar Elimination Programme in India, Nepal and Bangladesh?
QUESTION 59
Which feeding behaviour is described for female sandflies transmitting leishmaniasis?
QUESTION 60
Where do schistosomes mature after passing through the lungs and being carried to the liver?
QUESTION 61
A patient remains k39 strip-test positive several months after successful treatment of visceral leishmaniasis. Why is this result unsuitable for establishing relapse?
QUESTION 62
During the human phase of the Leishmania life cycle, in which cells do parasites transform into amastigotes?
QUESTION 63
Which severe necrotising soft tissue infection is primarily confined to subcutaneous fascia and fat?
QUESTION 64
Which antifungal may be used as oral step-down therapy for mucormycosis?
QUESTION 65
In the illustrated case of disseminated histoplasmosis presenting with diffuse papular rash and fever, which procedure established the diagnosis?
QUESTION 66
Why is histopathological confirmation required in addition to culture when diagnosing mucormycosis?
QUESTION 67
How does the severity of seborrhoeic dermatitis change as the CD4 count falls in a patient with HIV?
QUESTION 68
A patient with HIV has seborrhoeic dermatitis presenting as scaly red patches in hairy areas. Which treatment combination is described as effective?
QUESTION 69
A patient develops neutropenia after haematopoietic stem cell transplantation and chemotherapy for relapsed leukaemia, followed by fever and skin nodules. In the described case, which organism was cultured from both skin lesions and blood?
QUESTION 70
When do specific anti-HIV antibodies typically appear in serum relative to symptom development in primary HIV infection?
QUESTION 71
A patient has a glandular fever-like illness. Which additional finding strongly suggests primary HIV infection?
QUESTION 72
Which investigation is specified for early diagnosis of primary HIV infection?
QUESTION 73
Which antibiotic combination is specified for group A streptococcal necrotising soft tissue infection?
QUESTION 74
Which combination of organisms is associated with Meleney gangrene?
QUESTION 75
Which ocular appearance characterises trachoma?
QUESTION 76
What mechanism may cause constipation in typhoid fever?
QUESTION 77
Which NRTI can exacerbate the reduced bone mineral density seen in people with HIV?
QUESTION 78
Which manifestation of brucellosis almost always requires surgical intervention in addition to antimicrobial therapy?
QUESTION 79
Compared with typhoid fever, which pattern characterises paratyphoid fever?
QUESTION 80
Which biopsy may be necessary to confirm cryptosporidiosis or microsporidiosis?
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