Study notes

Acute inflammatory vascular changes and leukocyte recruitment

Leukocyte killing, inflammatory mediators, and morphologic patterns

Chronic inflammation, systemic effects, and tissue regeneration

Scar formation, wound healing, and C-reactive protein

Mechanism and causes of an elevated erythrocyte sedimentation rate

Sites of acetylcholine neurotransmission

Local synthesis of acetylcholine

Acetylcholine synthesis, vesicular storage, release, and toxin effects

Cholinesterases and termination of acetylcholine action

Cholinoceptor classes and endothelial relaxation

Muscarinic receptor actions and distribution

Muscarinic receptor subtypes and their principal functions

Cardiac M2 signalling and nicotinic receptor subtypes

Functions of neuronal nicotinic receptors

Mechanisms of cholinergic drugs

Cholinergic alkaloids and classification of acetylcholine actions

Muscarinic actions of acetylcholine on the heart, vessels and smooth muscle

Muscarinic effects on glands and the eye

Nicotinic actions of acetylcholine on autonomic ganglia

Acetylcholine actions on skeletal muscle

Choline esters: central effects, interactions and selected uses

Additional pilocarpine uses and muscarine

Types of mushroom poisoning and actions of arecoline

Anticholinesterases: mechanism and chemical groups

Anticholinesterases: lipid solubility and enzyme interactions

Enzyme aging and pharmacological actions of anticholinesterases

Anticholinesterase effects on ganglia, circulation and skeletal muscle

Anticholinesterases: endplate and central nervous system effects

Anticholinesterases: peripheral effects, pharmacokinetics and individual agents

Selected anticholinesterases and precautions for their use

Miotics in glaucoma: muscle actions

Ocular uses and adverse effects of miotics

Myasthenia gravis: pathogenesis, symptoms and initial treatment

Myasthenia gravis: immunotherapy, crisis and anticholinesterase overdose

Edrophonium ameliorative test for myasthenia gravis

Diagnostic and therapeutic uses of anticholinesterases

Cerebroselective anticholinesterases and onset of poisoning

Clinical manifestations of anticholinesterase poisoning

Treatment of anticholinesterase poisoning: supportive care, atropine and oximes

Oxime therapy and chronic organophosphate neurotoxicity